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Overview
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Calculated MW: 48 kDa/56 kDa/57 kDa/58 kDa/62 kDa
Observed MW: 57 kDa/58 kDaPlease contact us at for specific academic pricing.
Background
This gene encodes a member of the eyes absent (EYA) family of proteins. The encoded protein may act as a transcriptional activator and have a role during development. It can act as a mediator of chemoresistance and cell survival in Ewing sarcoma cells, where this gene is up-regulated via a micro-RNA that binds to the 3' UTR of the transcript. A similar protein in mice acts as a transcriptional activator. Alternative splicing of this gene results in multiple transcript variants.
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