Extrem A Diamond - Protein A Affinity Resins

Extrem A Diamond is an innovative enhanced alkali-resistant resin independently developed by Bestchrom. The protein A ligand is expressed in E. coli. Compared with previous AT Protein A Diamond Plus, it enjoys higher tolerance towards alkali (can tolerate CIP with 0.5-1.0M NaOH) and higher binding capacity. It can effectively cut cost during scale-up by choosing lower column volume. Besides, It is suitable for capturing monoclonal antibodies or Fc fusion protein from large volume cell culture media, as well as the capture of polyclonal antibodies from ascites or plasma.
The resin has the following characteristics:
▪ Under the same residence time, it has higher dynamic binding capacity than conventional products.
▪ The high alkaline tolerance of protein ligands can withstand CIP of 0.5~1.0M NaOH during the cleaning process.
▪ High binding capacity, reduced production cost and improved production efficiency.

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