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Overview
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Calculated MW: 70 kDa
Observed MW: Refer to figures
Gene Accession: BC001962Please contact us at for specific academic pricing.
Background
Exonuclease required for double-strand breaks resection and efficient homologous recombination. Plays a key role in controlling the initial steps of chromosomal break repair, it is recruited to chromatin in a damage-dependent manner and functionally interacts with the MRN complex to accelerate resection through its 3'-5' exonuclease activity, which efficiently processes double-stranded DNA substrates containing nicks.
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