Name: EWSR1 Polyclonal Antibody (1.08 mg/mL) for WB, IHC, ELISA
Price: 253.00 USD

Overview
- Calculated MW: 68 kDa
  Observed MW: Refer to figures
  Gene Accession: BC000527
  
  Please contact us at for specific academic pricing.
  
  Background
  
  This gene encodes a multifunctional protein that is involved in various cellular processes, including gene expression, cell signaling, and RNA processing and transport. The protein includes an N-terminal transcriptional activation domain and a C-terminal RNA-binding domain. Chromosomal translocations between this gene and various genes encoding transcription factors result in the production of chimeric proteins that are involved in tumorigenesis. These chimeric proteins usually consist of the N-terminal transcriptional activation domain of this protein fused to the C-terminal DNA-binding domain of the transcription factor protein. Mutations in this gene, specifically a t(11;22)(q24;q12) translocation, are known to cause Ewing sarcoma as well as neuroectodermal and various other tumors. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 1 and 14.
Properties
- Host
  
  rabbit
  
  Antibody Type
  
  polyclonal
  
  Isotype
  
  IgG
  
  Reactivity
  
  human; mouse
  
  Immunogen
  
  Fusion protein of human EWSR1
  
  Purification
  
  Antigen affinity purification
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
  
  Storage
  
  Store at -20°C. Avoid freeze-thaw cycles.
  
  Concentration
  
  1.08 mg/mL
  
  Antigen
  
  bK984G1.4, bK984G1.4 Ewing sarcoma breakpoint region 1 protein, Ewing sarcoma breakpoint region 1, Ewing sarcoma breakpoint region 1 protein, Ewings sarcoma EWS Fli1 type 1 oncogene, EWS, EWS oncogene, EWS RNA binding protein 1, EWS, EWSR 1, Ewsr1, EWSR1 protein, RNA binding protein EWS, RNA-binding protein EWS (UniProt:Q01844)
  
  * For reference only.

Applications

Application

WB; IHC; ELISA

Application	Dilutions
WB	1:1000-1:5000
IHC	1:50-1:300
ELISA	1:5000-1:10000

EWSR1 Polyclonal Antibody (1.08 mg/mL) for WB, IHC, ELISA

EWSR1 Polyclonal Antibody (1.08 mg/mL) for WB, IHC, ELISA

Background

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