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Overview
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Ethambutol is a unique slightly soluble (7.58 mg/mL) antitubercular antibiotic which inhibits cell wall formation in Mycobacterium species.
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Background
Ethambutol inactivates arabinosyl transferase, an enzyme responsible for transporting mycolic acids to the cell wall. Without this enzyme, cell permeability is increased leaving the oraganism vulnerable to toxic matter.
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- Properties
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Overview