ERCC5/XPG Rabbit Polyclonal Antibody

ERCC5/XPG Rabbit Polyclonal Antibody

Catalog Number:
A001450179ZEN
Mfr. No.:
Zen-370105
Price:
  • Size:
    100μl
    Quantity:
    Add to Cart:
      • Overview
        • Please contact us at for specific academic pricing.

          Background

          Seven complementation groups (A-G) of xeroderma pigmentosum have been described. The xeroderma pigmentosum group A protein, XPA, is a zinc metalloprotein which preferentially binds to DNA damaged by ultraviolet (UV) radiation and chemical carcinogens. XPA is a DNA repair enzyme that has been shown to be required for the incision step of nucleotide excision repair. XPG (also designated ERCC5) is an endonuclease that makes the 3’ incision in DNA nucleotide excision repair. Mammalian XPG is similar in sequence to yeast RAD2. Conserved residues in the catalytic center of XPG are important for nuclease activity and function in nucleotide excision repair.

      • Properties
        • Host
          rabbit
          Isotype
          IgG
          Reactivity
          human
          Immunogen
          Synthetic peptide corresponding to Human ERCC5/XPG.
          Purification
          Affinity Purified
          Conjugate
          Unconjugated
          Formulation
          1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.
          Storage
          Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
          Antigen
          (Gene ID:2073; UniProt:P28715)

          * Research Use Only Product (RUO). Not for Diagnosis or Therapeutic Use.

      • Applications
        • Application
          WB; IHC-P
        • Application Dilutions
          WB 1/500-1/1000
          IHC 1/50-1/200

    Note: If you don't receive our verification email, do the following:

    • Confirm that you entered your email address correctly.
    • Check if the email is in your spam or junk folder.
    • Or you may contact us at .
    Copyright © Amerigo Scientific. All rights reserved.