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Overview
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EPO a Human Recombinant produced in E. Coli is a single, non-glycosylated polypeptide chain containing 189 amino acids (28-193a.a.) and having a molecular mass of 20.9kDa. EPO a is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. EPO a is a member of the EPO/TPO family and encodes a secreted, glycosylated cytokine composed of four alpha helical bundles. EPO a is found in the plasma and regulates red cell production by promoting erythroid differentiation and initiating hemoglobin synthesis. EPO a also has neuroprotective activity against a variety of potential brain injuries and antiapoptotic functions in several tissue types.
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Overview