EIF4EBP1 Polyclonal Antibody (1 mg/mL) for IHC, IF

EIF4EBP1 Polyclonal Antibody (1 mg/mL) for IHC, IF

Catalog Number:
A001509617RED
Mfr. No.:
RD266892A
Price:
$347
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      • Overview
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          Background

          This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation.

      • Properties
        • Host
          rabbit
          Isotype
          IgG
          Reactivity
          human; mouse; rat
          Immunogen
          A synthetic peptide of human EIF4EBP1 (NP_004086.1).
          Purification
          Affinity purification
          Conjugate
          Unconjugated
          Formulation
          PBS with 0.02% sodium azide, 50% glycerol, pH7.3
          Storage
          Store at -20°C. Avoid freeze-thaw cycles.
          Concentration
          1 mg/mL
          Antigen
          4E-BP1, 4EBP1, BP-1, PHAS-I, EIF4EBP1 (Gene ID:1978; UniProt:Q13541)

          * For reference only.

      • Applications
        • Application
          IHC; IF
        • Application Dilutions
          IHC 1:50-1:200
          IF 1:50-1:200

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