EIF2AK3 Polyclonal Antibody

EIF2AK3 Polyclonal Antibody

Catalog Number:
A001509754RED
Mfr. No.:
RD267315A
Price:
$347
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      • Overview
        • Calculated MW: 125 kDa
          Observed MW: 160 kDa

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          Background

          The protein encoded by this gene phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2, leading to its inactivation, and thus to a rapid reduction of translational initiation and repression of global protein synthesis. This protein is thought to modulate mitochondrial function. It is a type I membrane protein located in the endoplasmic reticulum (ER), where it is induced by ER stress caused by malfolded proteins. Mutations in this gene are associated with Wolcott-Rallison syndrome.

      • Properties
        • Host
          rabbit
          Isotype
          IgG
          Reactivity
          human; mouse; rat
          Immunogen
          Recombinant protein of human EIF2AK3
          Purification
          Affinity purification
          Conjugate
          Unconjugated
          Formulation
          PBS with 0.02% sodium azide, 50% glycerol, pH7.3
          Storage
          Store at -20°C. Avoid freeze-thaw cycles.
          Concentration
          1 mg/mL
          Antigen
          EIF2AK3, PEK, PERK, WRS (Gene ID:9451; UniProt:Q9NZJ5)

          * For reference only.

      • Applications
        • Application
          WB
        • Application Dilutions
          WB 1:500-1:2000

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