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Overview
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Background
EGTA, also known as egtazic acid, is an aminopolycarboxylic acid, a calcium chelator. It can protects against cell death caused by nitric oxide-induced calcium influx into nerve cells[1,2].
[1]. Boullerne A I, Nedelkoska L, Benjamins J A. Role of calcium in nitric oxide-induced cytotoxicity: EGTA protects mouse oligodendrocytes. Journal of Neuroscience Research, 2001, 63(2): 124-135.
[2]. Fisher A E O, Hague T A, Clarke C L, et al. Catalytic superoxide scavenging by metal complexes of the calcium chelator EGTA and contrast agent EHPG. Biochemical and Biophysical Research Communications, 2004, 323(1): 0-167.
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