EGFR(Phospho-Tyr1092) Antibody

EGFR(Phospho-Tyr1092) Antibody

Catalog Number:
A001548109RED
Mfr. No.:
RDSA62084
Price:
$483
  • Size:
    100μL
    Quantity:
    Add to Cart:
      • Overview
        • Please contact us at for specific academic pricing.

          Background

          Receptor for EGF, but also for other members of the EGF family, as TGF-a, amphiregulin, betacellulin, heparin-binding EGF-like growth factor, GP30 and vaccinia virus growth factor. Is involved in the control of cell growth and differentiation. Phosphorylates MUC1 in breast cancer cells and increases the interaction of MUC1 with SRC and CTNNB1/beta-catenin.

      • Properties
        • Host
          rabbit
          Antibody Type
          polyclonal
          Isotype
          IgG
          Reactivity
          human; rat
          Immunogen
          Peptide sequence around phosphorylation site of tyrosine1092 (P-E-Y(p)-I-N) derived from Human EGFR.
          Purification
          Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatography using non-phosphopeptide.
          Conjugate
          Unconjugated
          Formulation
          Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
          Storage
          Store at -20°C. Avoid freeze / thaw cycles.
          Concentration
          1.0 mg/mL
          Antigen
          ERBB1;Receptor protein-tyrosine kinase ErbB-1;kinase EGFR (Gene ID:1956; UniProt:P00533)

          * This product is for Research Use Only.

      • Applications
        • Application
          WB; IHC
        • Application Dilutions
          WB 1:500-1:1000
          IHC 1:50-1:100

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