Name: E70K
Price: 298.00 USD

- Overview
  - Inhibits CXCL8-induced neutrophil transendothelial migration.
    E70K, also known as peptide 2, is the C-terminal CXCL8 peptide fragment CXCL8 (54-72), with a glutamic acid (E) substituted at position 70 with lysine (K) to increase positive charge. Similarly to CXCL8 (54-72), E70K inhibits CXCL8-induced neutrophil transendothelial migration and provides a lead for further development of therapeutic inhibitors of neutrophil-mediated inflammation based on modulation of chemokine GAG binding.
    
    Please contact us for availability.
    
    Please contact us at for specific academic pricing.
- Properties
  - Categories
    
    Peptides
    
    Alternative Name
    
    Peptide 2
    
    Molecular Formula
    
    C108H178N34O28
    
    Molecular Weight
    
    2400.81
    
    Appearance
    
    Freeze dried solid
    
    Purity
    
    >95% by HPLC
    
    Solubility
    
    Soluble in physiological buffers including PBS (>1mg./mL). Soluble in DMSO as a stock solution.
    
    Other Properties
    
    Sequence: Ac-Lys-Glu-Asn-Trp-Val-Gln-Arg-Val-Val-Glu-Lys-Phe-Leu-Lys-Arg-Ala-Lys-Asn-Ser-NH2,Ac-KENWVQRVVEKFLKRAKNS-NH2
    Modification: N terminal acetylation, C terminal amide
    
    Storage
    
    Store dry, frozen and in the dark
    
    * Please note: this product can only be supplied to registered research and development facilities, and may be used for in vitro research use only, not for administration to humans or animals.

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