DPQ

DPQ

Catalog Number:
FC01366306APE
Mfr. No.:
APE-B7934
Price:
$198
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      • Overview
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          Background

          DPQ is a potent inhibitor of PARPs, inhibiting PARP1 with an IC50 value of 40 nM. It is approximately 10-fold less potent against PARP2. DPQ can be used in either cells or in animals.

      • Properties
        • Alternative Name
          5-(4-(piperidin-1-yl)butoxy)-3,4-dihydroisoquinolin-1(2H)-one
          CAS Number
          129075-73-6
          Molecular Formula
          C18H26N2O2
          Molecular Weight
          302.41
          Appearance
          A white to off-white solid
          Purity
          98.00%
          Solubility
          Soluble in DMSO
          Storage
          Store at -20°C
          SMILES
          O=C1NCCC2=C(C=CC=C21)OCCCCN3CCCCC3

          * For Research Use Only

      • Reference
        • 1. Cao S, Sun Y, et al. "Poly (ADP-ribose) polymerase inhibition protects against myocardial ischaemia/reperfusion injury via suppressing mitophagy." J Cell Mol Med. 2019 Aug 5. PMID:31379115

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