DON-NIV WB Immunoaffinity Column

Monoclonal antibodies enable the DON-NIV WB immunoaffinity column to isolate DON and NIV simultaneously from a single sample extract. Its 3 mL, wide-bore construction delivers flow-through speed to this powerful sample preparation column. Coupled with LC for detection, DON-NIV WB doubles the productivity of traditional laboratory analysis for DON and NIV.

Benefits
• High Recovery – Over 90% for deoxynivalenol and nivalenol*
• Exclusive – Primarily for HPLC or UPLC use
• Convenient – Total readings for deoxynivalenol and nivalenol
• Durable – Long shelf life
• Versatility – For use with wheat and other commodities
• Large Volume - Column size of 3 mL
• Quick – 15 minutes to isolate toxins**
• Simple – Easy-to-use procedure
* Using procedure developed by VICAM
**excluding preparation and extraction

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Background

Deoxynivalenol (DON) is also known as vomitoxin because of its impact on livestock through interference with animal growth and acceptance of feed. DON has been implicated in moldy corn toxicosis of swine. DON is often present with other mycotoxins and has been isolated from grains and feeds throughout the world at levels as high as 92 ppm. Because of concerns about DON, the United States FDA has instituted advisory levels of 1 ppm for wheat products for human consumption, 5 ppm for grain products for most animal feeds and 10 ppm for grain products for cattle feed. The European Community has regulations for DON levels that range from less than 0.2 ppm in processed cereal based foods for infants and young children to less than 1.75 ppm for unprocessed wheat.