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Overview
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Calculated MW: 29kDa/50kDa/54kDa/57kDa/59kDa
Observed MW: 60kDaPlease contact us at for specific academic pricing.
Background
CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated.
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