DNA-RNA Hybrid [S9.6] Mouse Monoclonal Antibody

DNA-RNA Hybrid [S9.6] Mouse Monoclonal Antibody

Catalog Number:
A001449983ZEN
Mfr. No.:
Zen-230053
Price:
  • Size:
    100μl
    Quantity:
    Add to Cart:
      • Overview
        • Please contact us at for specific academic pricing.

          Background

          The DNA-RNA hybrids are a natural occurrence within eukaryotic cells and their level are high at sites of high transcriptional activity.They are non-canonical nucleic acid structures with transcriptional regulatory functions. Their presence is reported to predispose a locus to chromosomal breakage. The S9.6 monoclonal antibody recognizes DNA-RNA hybrids (also known as R-loops) and does not bind to single or double stranded DNA.

      • Properties
        • Host
          mouse
          Isotype
          IgG2a
          Reactivity
          all
          Immunogen
          ΦX174 bacteriophage-derived synthetic DNA/RNA
          Purification
          Affinity Purified
          Conjugate
          Unconjugated
          Formulation
          Liquid in PBS containing 50% glycerol, 0.5% BSA, pH 7.3.
          Storage
          Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

          * Research Use Only Product (RUO). Not for Diagnosis or Therapeutic Use.

      • Applications
        • Application
          ICC/IF; IP; ChIP
        • Application Dilutions
          IF 1/50-1/200
          IP 1/50-1/300
          ChIP 1/20

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