Name: DMPO
Price: 446.00 USD

- Overview
  - Because of potential cancer risks and their age-promoting effects, free radicals in living bodies have become a frequently studied subject. DMPO is the most frequently used spin-trapping reagent for the study of free radicals. It is suitable for trapping oxygen radicals, especially superoxides, and for producing adducts with characteristic EPR (ESR) patterns. However, most commercially available DMPO contains impurities that cause high backgrounds. Thus, DMPO requires further purification for running experiments on EPR. The quality of Dojindo’s DMPO is well controlled and Dojindo’s DMPO doesn’t require any pre-purification process. There are no impurities to cause a background problem.
    
    Please contact us at for specific academic pricing.
- Properties
  - Categories
    
    Spin Trap Reagent
    
    CAS Number
    
    3317-61-1
    
    Molecular Formula
    
    C6H11NO
    
    Molecular Weight
    
    113.16
    
    Appearance
    
    Colorless liquid
    
    Purity
    
    ≥99.0%(GC)
    
    Storage
    
    -20°C, protect from light and moisture
    
    Shipping
    
    with blue ice
    
    * For research use only
- Reference
  - Current Publication Using This Product
    
    Tresp, H., Hammer, M. U., Weltmann, K.-D., Reuter, S.; 2014; Effects of Atmosphere Composition and Liquid Type on Plasma Generated Reactive Species in Biologically Relevant Solutions; DOI:10.1615/PlasmaMed.2014009711
    
    1) S. Sankarapandi, et al., Evidence against the generation of free hydroxyl radicals from the interaction of copper,zinc-superoxide dismutase and hydrogen peroxide. J Biol Chem. 1999;274:34576-34583.
    
    2) H. Li, et al., A pyrroline derivative of mexiletine offers marked protection against ischemia/reperfusion-induced myocardial contractile dysfunction. J Pharmacol Exp Ther. 2000;295:563-571.
    
    3) H. P. Souza, et al., Quantitation of superoxide generation and substrate utilization by vascular NAD(P)H oxidase. Am J Physiol Heart Circ Physiol. 2002;282:H466-H474.
    
    4) S. Kaewpila, et al., Manganese superoxide dismutase modulates hypoxia-inducible factor-1 alpha induction via superoxide. Cancer Res. 2008;68:2781-2788.
    
    5) M. L. T. Teoh, et al., Overexpression of extracellular superoxide dismutase attenuates heparanase expression and inhibits breast carcinoma cell growth and invasion. Cancer Res. 2009;69:6355-6363.
    
    6) Y. Song, et al., Nonenzymatic displacement of chlorine and formation of free radicals upon the reaction of glutathione with PCB quinones. PNAS. 2009;106:9725-9730.

MSDS

DMPO

DMPO

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