DiBAC4(3)

- Overview
  - DiBAC4(3) is a Bis-oxonol-type, membrane-potential, sensitive dye. According to membrane depolarization detection, when DiBAC distribution in cytosol is increased, the fluorescence intensitiy is increased. Since an argon laser (488 nm) can be used for DiBAC4(3) excitation, it is applicable for flow cytometry and confocal microscopy.
    
    Please contact us at for specific academic pricing.
- Properties
  - Categories
    
    Intracellular Fluorescent Probes
    
    Molecular Formula
    
    C27H39N4NaO6
    
    Molecular Weight
    
    538.61
    
    Appearance
    
    Reddish-orange to red powder
    
    Purity
    
    ≥98.0% (HPLC)
    
    Storage
    
    0-5°C
    
    Shipping
    
    ambient temperature
    
    * For research use only
- Reference
  - 1) D. E. Epps, et al., Characterization of the Steady-state and Dynamic Fluorescence Properties of the Potential-sensitive Dye Bis-(1,3-dibutylbarbituric acid)trimethine oxonol(Dibac4(3)) in Model Systems and Cells. Chem Phys Lipids. 1994;69:137-150.
    
    2) T. Brauner, et al., Comparative Measurements of Membrane Potentials with Microelectrodes and Voltage-sensitibe Dyes. Biochim Biophys Acta. 1984;771:208-216.
    
    3) T. T. Rohn, et al., Xanthine Affects [Ca2+]i and Contractile Responses of Ventricular Cardiocytes to Electrical Stimulation. Am J Physiol. 1997;273:C909-C917.
    
    4) D. J. Mason, et al., Rapid Estimation of Bacterial Antibiotic Susceptibility with Flow Cytometry. J Microsc. 1994;176:8-16.
    
    5) U. Langheinrich, et al., Hyperpolarization of Isolated Capillaries from Guinea-pig Heart Induced by K+ Channel Openers and Glucose Deprivation. J Physiol. 1997;502:397-408.
    
    6) K. S. Schroeder, et al., FLIPR: A New Instrument for Accurate, High Throughput Optical Screening. J Biomol Screen. 1996;1:75-80.

MSDS

DiBAC4(3)

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