Deoxycorticosterone acetate

- Overview
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    Background
    
    Deoxycorticosterone acetate is a steroid hormone used for intramuscular injection for replacement therapy of the adrenocortical steroid.
- Properties
  - Categories
    
    Steroid hormone
    
    Alternative Name
    
    [2-[(8S,9S,10R,13S,14S,17S)-10,13-dimethyl-3-oxo-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] acetate
    
    CAS Number
    
    56-47-3
    
    Molecular Formula
    
    C23H32O4
    
    Molecular Weight
    
    372.5
    
    Appearance
    
    A solid
    
    Purity
    
    98.00%
    
    Solubility
    
    insoluble in H2O; insoluble in EtOH; ≥16.4 mg/mL in DMSO
    
    Storage
    
    Store at -20°C
    
    SMILES
    
    O=C(COC(C)=O)[[email protected]@H]1[[email protected]](CC2)(C)[[email protected]@H](CC1)[[email protected]](CC3)[[email protected]]2[[email protected]](CC4)(C)C3=CC4=O
    
    * For Research Use Only
- Reference
  - 1. Yan Lu, E Wang, et al. "Obesity-induced excess of 17-hydroxyprogesterone promotes hyperglycemia through activation of glucocorticoid receptor." J Clin Invest. 2020 Jul 1;130(7):3791-3804. PMID:32510471