Cyproterone Acetate

- Overview
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    Background
    
    Cyproterone acetate has antagonistic properties towards the androgen receptor with an IC50 value of 7.1 nM. It can however, also act as a partial agonist of AR at an EC50 of 4.0 μM.
- Properties
  - Categories
    
    Androgen receptor antagonist
    
    Alternative Name
    
    (1aR,5aR,5bS,8R,8aS,10aS,10bS,10cS)-8-acetyl-4-chloro-8a,10b-dimethyl-2-oxo-1,1a,2,5a,5b,6,7,8,8a,9,10,10a,10b,10c-tetradecahydrocyclopenta[a]cyclopropa[g]phenanthren-8-yl acetate
    
    CAS Number
    
    427-51-0
    
    Molecular Formula
    
    C24H29ClO4
    
    Molecular Weight
    
    416.94
    
    Appearance
    
    A solid
    
    Purity
    
    98.00%
    
    Solubility
    
    insoluble in H2O; ≥14.7 mg/mL in DMSO; ≥20.55 mg/mL in EtOH
    
    Storage
    
    Store at -20°C
    
    SMILES
    
    ClC1=C([H])C(C(C([H])([H])C2([H])[H])([H])C(C2(C(C([H])([H])[H])=O)OC(C([H])([H])[H])=O)(C([H])([H])[H])C([H])([H])C3([H])[H])([H])C3([H])C(C1=C([H])C4=O)(C([H])([H])[H])C5([H])C4([H])C5([H])[H]
    
    * For Research Use Only