Name: CyFlow™ HLA-DR1 (empty) Purified
Price: 306.00 USD

- Overview
  - Please contact us at for specific academic pricing.
    
    Background
    
    HLA-DR1 belongs to the HLA class II β chain paralogues. The MHC Class II molecule is a heterodimer consisting of an α (DRA) and a β chain (DRB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. MHC Class II molecules are expressed in antigen presenting cells (APC). The β chain is approximately 26-28 kDa. Within the DR molecule the β chain contains all the polymorphisms specifying the peptide binding specificities. Hundreds of DRB1 alleles have been described and typing for these polymorphisms is routinely done for bone marrow and kidney transplantation.
- Properties
  - Host
    
    mouse
    
    Antibody Type
    
    monoclonal
    
    Isotype
    
    IgG2b
    
    Reactivity
    
    human
    
    Clone
    
    MEM-267
    
    Immunogen
    
    Purified, insoluble DR1 β chain (DRB1*0101) expressed in E. coli inclusion bodies
    
    Conjugate
    
    Purified
    
    Formulation
    
    The reagent is provided in phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.09% (w/v) sodium azide.
    
    Storage
    
    Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
    
    Concentration
    
    1 mg/mL
    
    Regulatory Status
    
    RUO
    
    * Research use only
- Applications
  - Application
    
    ELISA; Flow Cytometry; WB