Name: CyFlow™ CD71 APC-Cy7
Price: 773.00 USD

- Overview
  - CD71 (T9, TFR, TRFR) is a type II transmembrane glycoprotein expressed as homodimer in erythroid blood cell line and in activated leukocytes. Upon binding of holotransferrin (complex of transferrin and iron ions), CD71 is internalized by clathrin-mediated endocytosis. Acidification of endosomes by vesicular membrane proton pumps leads to dissociation of iron ions, whereas transferrin (apotransferrin) remains associated with CD71 and recycles to the cell surface, where it is released upon exposure to normal pH. CD71 is also involved in uptake of non-transferrin bound iron.
    
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- Properties
  - Host
    
    mouse
    
    Antibody Type
    
    monoclonal
    
    Isotype
    
    IgG1
    
    Reactivity
    
    human
    
    Clone
    
    MEM-75
    
    Immunogen
    
    NALM-6 human pre-B cell line
    
    Conjugate
    
    APC/Cyanine7
    
    Formulation
    
    The reagent is provided in stabilizing phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.09% (w/v) sodium azide.
    
    Storage
    
    Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
    
    Concentration
    
    50 µg/mL
    
    Regulatory Status
    
    ASR
    
    Antigen
    
    T9 , TFR, TRFR
- Applications
  - Application
    
    Flow Cytometry
    
    Application Description
    
    The reagent may have application in various test methodologies, including Flow Cytometry. Vial has sufficient volume for 100 tests, if used at 10 μL·/·test. User has responsibility for determining reagent quantity per test for any ASR reagent.
    
    Emission Maximum: 780 nm
    Excitation Maximum: 650 nm, 750 nm