CyFlow™ CD263 Azide Free

CyFlow™ CD263 Azide Free

Catalog Number:
A001343493SYS
Mfr. No.:
AE050786
Price:
$306
  • Size:
    0.1 mg (0.1 mL)
    Quantity:
    Add to Cart:
      • Overview
        • Please contact us at for specific academic pricing.

          Background

          CD263 (TRAIL-R3, TR3, DcR1, LIT, TRID), expressed mainly on neutrophils, belongs to receptors of TRAIL, a TNF-like membrane cytotoxic protein that induces apoptosis in many tumor cells, but not in normal cells. TRAIL-R3, however, is a GPI-anchored protein that lacks cytoplasmic death domain, thus it is unable to induce apoptosis and serves as a negative regulator of apoptotic signaling by competing for binding of TRAIL with death receptor 5 (DR5).

      • Properties
        • Host
          mouse
          Antibody Type
          monoclonal
          Isotype
          IgG1
          Reactivity
          human
          Clone
          TRAIL-R3-02
          Immunogen
          TRAIL-R3 (aa 1-280) - hIgGhc fusion protein
          Conjugate
          Azide Free
          Formulation
          The reagent is provided in azide-free phosphate buffered saline (PBS) solution, pH ≈7.4; 0.2 µm filter sterilized.
          Storage
          Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
          Concentration
          1 mg/mL
          Regulatory Status
          RUO
          Antigen
          DCR1, LIT, TNFRSF10c, TRAILR3 , TRID

          * Research use only

      • Applications
        • Application
          Flow Cytometry

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