CyFlow™ CD16 Azide Free

CyFlow™ CD16 Azide Free

Catalog Number:
A001343261SYS
Mfr. No.:
BV863782
Price:
$306
  • Size:
    0.1 mg (0.1 mL)
    Quantity:
    Add to Cart:
      • Overview
        • Please contact us at for specific academic pricing.

          Background

          CD16 (FcγRIII) is a 50-65 kDa glycoprotein serving as a low affinity IgG receptor. Human FcγRIII is expressed in two forms - FcγRIIIA and FcγRIIIB. FcγRIIIA is a transmembrane protein of monocytes, macrophages, NK cells and a subset of T cells. It is associated with FcεRI-γ subunit and is responsible for antibody-dependent NK cell cytotoxicity. Mast cell FcγRIIIA is associated, moreover, with FcεRI-β subunit. Besides IgG, FcγRIIIA can be triggered also by oligomeric IgE. FcγRIIIB is a GPI-linked monomeric receptor expressed on neutrophils and is involved in their activation and induction of a proadhesive phenotype.

      • Properties
        • Host
          mouse
          Antibody Type
          monoclonal
          Isotype
          IgG1
          Reactivity
          human
          Clone
          MEM-154
          Immunogen
          Human granulocytes
          Conjugate
          Azide Free
          Formulation
          The reagent is provided in azide-free phosphate buffered saline (PBS) solution, pH ≈7.4; 0.2 µm filter sterilized.
          Storage
          Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
          Concentration
          1 mg/mL
          Regulatory Status
          RUO
          Antigen
          FcγRIII

          * Research use only

      • Applications
        • Application
          Flow Cytometry; Functional Assays; Immunoprecipitation; WB

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