Name: CyFlow™ CD154 Low Endotoxin
Price: 324.00 USD

- Overview
  - Please contact us at for specific academic pricing.
    
    Background
    
    CD154 / CD40L (CD40 ligand) is a member of the tumor necrosis factor family, and is expressed primarily on activated CD4+ lymphocytes, but also on mast cells, basophils, eosinophils and human dendritic cells. Its counter-receptor CD40 is expressed on antigen presenting cells, including dendritic cells, macrophages, and B cells, and also on fibroblasts. Triggering of CD40 by CD40L causes maturation of dendritic cells and upregulation of antigen presentation in functions of the MHC and costimulatory molecules. CD40L also functions as a direct stimulating factor for T cells. CD40L plays also roles e.g. in antibody class switching and modulation of apoptosis in the germinal center.
- Properties
  - Host
    
    mouse
    
    Antibody Type
    
    monoclonal
    
    Isotype
    
    IgG1
    
    Reactivity
    
    human; non-human primates
    
    Clone
    
    24-31
    
    Immunogen
    
    Human CD154 fusion protein
    
    Conjugate
    
    Low Endotoxin
    
    Formulation
    
    The reagent is provided in azide-free phosphate buffered saline (PBS) solution, pH ≈7.4; 0.2 µm filter sterilized. Endotoxin level is less than 0.01 EU/µg of the protein, as determined by the LAL test.
    
    Storage
    
    Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
    
    Concentration
    
    1 mg/mL
    
    Regulatory Status
    
    RUO
    
    Antigen
    
    CD40L , gp39, IMD3, T-BAM, TNFSF5, TRAP-1
    
    * Research use only
- Applications
  - Application
    
    Flow Cytometry; Functional Assays; Immunocytochemistry

Datasheet

MSDS

CyFlow™ CD154 Low Endotoxin

CyFlow™ CD154 Low Endotoxin

Background

We Also Recommend

CyFlow™ CD152 PE

CyFlow™ CD152 Purified

CyFlow™ CD154 FITC