Name: CyFlow™ CD13 Low Endotoxin
Price: 324.00 USD

- Overview
  - Please contact us at for specific academic pricing.
    
    Background
    
    CD13 (APN; aminopeptidase N) is a 150 kDa type II transmembrane zinc-binding ectopeptidase expressed on various cell types. This metalloprotease preferentially catalyzes removal of neutral amino acids from small peptides, thus activating or inactivating bioactive peptides. CD13 has also role in extracellular matrix degradation, antigen processing and signal transduction, is important in inflammatory responses, regulates intercellular contact, cell motility and vascularization. CD13 is involved in protection of leukemic cells against apoptosis and its expression associated with poor prognosis of carcinomas.
- Properties
  - Host
    
    mouse
    
    Antibody Type
    
    monoclonal
    
    Isotype
    
    IgG1
    
    Reactivity
    
    human; non-human primates
    
    Clone
    
    WM15
    
    Immunogen
    
    Human Acute Myelogenous Leukemia (AML) cells
    
    Conjugate
    
    Low Endotoxin
    
    Formulation
    
    The reagent is provided in azide-free phosphate buffered saline (PBS) solution, pH ≈7.4; 0.2 µm filter sterilized. Endotoxin level is less than 0.01 EU/µg of the protein, as determined by the LAL test.
    
    Storage
    
    Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
    
    Concentration
    
    1 mg/mL
    
    Regulatory Status
    
    RUO
    
    Antigen
    
    APN , gp150
    
    * Research use only
- Applications
  - Application
    
    Flow Cytometry; Functional Assays; IHC (frozen); Immunoprecipitation