CyFlow™ CD123 PE-Cy5

CyFlow™ CD123 PE-Cy5

Catalog Number:
A001343144SYS
Mfr. No.:
CG493432
Price:
$536
  • Size:
    100 tests (0.4 mL)
    Quantity:
    Add to Cart:
      • Overview
        • Please contact us at for specific academic pricing.

          Background

          CD123 is the α chain of interleukin 3 receptor (IL-3R α). This subunit heterodimerizes with the interleukin 3 receptor β chain (CD131), which is shared with other receptors. CD123 interacts with IL-3 specifically, but with low affinity, and association with the β subunit confers high affinity binding to the receptor heterodimer. Both chains are required for signaling, but receptor activation and signal transduction depend on IL-3 binding to CD123 as the initial step.

      • Properties
        • Host
          mouse
          Antibody Type
          monoclonal
          Isotype
          IgG1
          Reactivity
          human
          Clone
          6H6
          Immunogen
          IL3 receptor α chain expressed on the surface of transiently transfected COS cells
          Conjugate
          PE/Cyanine5
          Formulation
          The reagent is provided in stabilizing phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.09% (w/v) sodium azide.
          Storage
          Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
          Regulatory Status
          RUO
          Antigen
          IL-3Ra , IL3R

          * Research use only

      • Applications
        • Application
          Flow Cytometry
          Application Description
          The reagent is designed for Flow Cytometry analysis of human blood cells. Recommended usage is 4·µl reagent·/ 100·µl of whole blood or 10^6 cells in a suspension. The content of a vial (0.4 ml) is sufficient for 100 tests.

          Emission Maximum: 670 nm
          Excitation Maximum: 496 nm, 565 nm

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