CyFlow™ CD117 Biotin

CyFlow™ CD117 Biotin

Catalog Number:
A001343073SYS
Mfr. No.:
BJ868997
Price:
$378
  • Size:
    0.1 mg (0.1 mL)
    Quantity:
    Add to Cart:
      • Overview
        • Please contact us at for specific academic pricing.

          Background

          CD117 (c-Kit) is a 145 kDa receptor tyrosine kinase that regulates cell proliferation, adhesion, chemotaxis, apoptosis and other cell processes. Mutations of CD117 can lead to growth and progression of tumors. After binding of its ligand, SCF (stem cell factor), CD117 is autophosphorylated on its intracellular domains and activated. CD117 is expressed on pluripotent hematopoietic progenitor cells, mast cells and various cancer cells, e.g. acute myeloid leukemia cells.

      • Properties
        • Host
          mouse
          Antibody Type
          monoclonal
          Isotype
          IgG1
          Reactivity
          cow; human; non-human primates
          Clone
          104D2
          Immunogen
          MOLM-1 megakaryocytic cells
          Conjugate
          Biotin
          Formulation
          The reagent is provided in phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.09% (w/v) sodium azide.
          Storage
          Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
          Concentration
          1 mg/mL
          Regulatory Status
          RUO
          Antigen
          c-kit , SCFR

          * Research use only

      • Applications
        • Application
          Flow Cytometry
          Application Description
          The reagent is designed for indirect immunofluorescence analysis by Flow Cytometry. Working concentrations should be determined by the investigator.

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