Cyclosporin B

Cyclosporin B

Catalog Number:
P004439904INV
Mfr. No.:
V18968
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      • Overview
        • Cyclosporin B is cyclic peptide immunosuppressant that has been used in organ transplantationfor the prevention of graft rejection. A group of nonpolar cyclic oligopeptides with immunosuppressant activity. Cyclosporin B is a analogue of cyclosporin A that exhibits significantly less immunosuppressive activity. Cyclosporin B exhibits antiviral properties, inhibiting entry of hepatitis B into hepatocytes. Cyclosporin B also inhibits RANKL-induced TRAP phosphatase activity, inducing apoptosis in osteoclasts.

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      • Properties
        • Categories
          Peptides
          CAS Number
          63775-95-1
          Molecular Formula
          C61H109N11O12
          Molecular Weight
          1188.6
          Purity
          ≥98%
          Storage
          Powder: store in -20°C freezer for up to three years, store in 4°C freezer for up to two years
          In solvent: store in -80°C freezer for up to six months, store in -20°C freezer for up to two months
          Shipping
          Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
          SMILES
          N1(C)[C@@]([H])([C@H](O)[C@H](C)C/C=C/C)C(=O)N[C@@H](C)C(=O)N(C)CC(=O)N(C)[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N(C)[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@H](C)C(=O)N(C)[C@@H](CC(C)C)C(=O)N(C)[C@@H](CC(C)C)C(=O)N(C)[C@@H](C(C)C)C1=O

          * For research use only

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