Cy3-UTP

- Overview
  - Please contact us at for specific academic pricing.
    
    Background
    
    Cy3-UTP (Cyanine 3-UTP) can replace UTP as a substrate for T7 RNA polymerase and generate labeled probes through in vitro transcription. The resulting assembled mRNA will emit orange fluorescence with the involvement of Cy3-UTPs. In addition, Cy3-labeled mRNA is readily visible under ultraviolet light without further staining after gel electrophoresis[1].
    Probes generated by these methods are suitable for multicolor fluorescence analysis, specifically dual-color expression arrays in conjunction with cyanine 3-UTP .
    Reference:
    [1]Kim, H., Park, Y., & Lee, J. B. (2015). Self-assembled Messenger RNA Nanoparticles (mRNA-NPs) for Efficient Gene Expression. Scientific Reports, 5(1). doi:10.1038/srep12737
- Properties
  - Categories
    
    used as a substrate for T7 RNA polymerase and generate labeled probes through in vitro transcription
    
    Alternative Name
    
    Aminoallyl-UTP - Cy3;5-(3-Aminoallyl)-uridine-5'-triphosphate; labeled with Cy3;Triethylammonium salt;Cyanine 3-AA-UTP;Cyanine 3-Aminoallyluridine-5'-Triphosphate;Cyanine 3-UTP; 2-((1E,3E)-3-(1-(6-(((E)-3-(1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(((hydroxy((hydroxy(phosphonooxy)phosphoryl)oxy)phosphoryl)oxy)methyl)tetrahydrofuran-2-yl)-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)allyl)amino)-6-oxohexyl)-3,3-dimethyl-5-sulfoindolin-2-ylid
    
    Molecular Formula
    
    C43H56N5O22P3S2(free acid)
    
    Molecular Weight
    
    1151.98 (free acid)
    
    Appearance
    
    Solution
    
    Purity
    
    95.00%
    
    Solubility
    
    Soluble in H2O
    
    Storage
    
    Store at -20°C or below
    
    SMILES
    
    O=S(C1=CC=C([N+](CC)=C(C2(C)C)/C=C/C=C(C(C)(C)C3=C4C=CC(S(O)(=O)=O)=C3)/N4CCCCCC(NC/C=C/C5=CN([[email protected]]6[[email protected]](O)[[email protected]](O)[[email protected]@H](COP(OP(O)(OP(O)(O)=O)=O)(O)=O)O6)C(NC5=O)=O)=O)C2=C1)([O-])=O
    
    * For Research Use Only
- Reference
  - 1. Lin Wu, Dian Chen, et al. "A transient conformation facilitates ligand binding to the adenine riboswitch." iScience. PMID: 34927032

Documents

COA (Certificate Of Analysis)

MSDS (Material Safety Data Sheet)

Cy3-UTP

Background

Documents

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