CUTA Polyclonal Antibody (1.2 mg/mL) for IHC, ELISA

CUTA Polyclonal Antibody (1.2 mg/mL) for IHC, ELISA

Catalog Number:
A001508076RED
Mfr. No.:
RD252563A
Price:
$253
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      • Overview
        • Gene Accession: BC005890

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          Background

          CUTA, also known as ACHAP (acetylcholinesterase-associated protein), is the 179 amino acid mammalian homolog of the cutA E. coli protein and is ubiquitously expressed, particularly in brain tissue. Existing as multiple alternatively spliced isoforms, CUTA functions as a homotrimer that is thought to act as a component of an acetylcholinesterase (AChE)-attached complex, suggesting an involvement in AChE regulation. The gene encoding CUTA maps to human chromosome 6, which contains 170 million base pairs and comprises nearly 6% of the human genome. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer, suggesting the presence of a cancer susceptibility locus. Additionally, Porphyria cutanea tarda, Parkinson’s disease, Stickler syndrome and a susceptibility to bipolar disorder are all associated with genes that map to chromosome 6.

      • Properties
        • Host
          rabbit
          Antibody Type
          polyclonal
          Isotype
          IgG
          Reactivity
          human
          Immunogen
          Fusion protein of human CUTA
          Purification
          Antigen affinity purification
          Conjugate
          Unconjugated
          Formulation
          PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
          Storage
          Store at -20°C. Avoid freeze-thaw cycles.
          Concentration
          1.2 mg/mL
          Antigen
          Acetylcholinesterase Associated Protein, Acetylcholinesterase-associated protein, ACHAP, Brain acetylcholinesterase putative membrane anchor, C6ORF82, cutA, CutA Divalent Cation Tolerance Homolog , cutA divalent cation tolerance homolog (E. coli), CUTA, CutA1, divalent cation tolerant protein CUTA, MGC111154, OTTHUMP00000039621, Protein CutA, RP4570F34 (UniProt:O60888)

          * For reference only.

      • Applications
        • Application
          IHC; ELISA
        • Application Dilutions
          IHC 1:40-1:200
          ELISA 1:5000-1:10000

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