Name: CTSL Recombinant Protein
Price: Inquiry

- Overview
  - CTSL Human Recombinant produced in E. Coli is a single,non-glycosylated polypeptide chain containing 339 amino acids (18-333 a.a) andhaving a molecular mass of 38.3kDa. CTSL is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. Cathepsin-L also known as CTSL is a member of the peptidase C1 family. CTSL, is a dimer composed of disulfide-linked heavy and light chains, bothformed from a single protein precursor. Furthermore, CTSL is a lysosomalcysteine proteinase which takes a main part in intracellular proteincatabolism. CTSL substrates include collagen and elastin, as well as alpha-1protease inhibitor, which is the most important controlling element ofneutrophil elastase activity. CTSL has been implicated in a number of pathologicprocesses, including myofibril necrosis in myopathies and in myocardialischemia, and in the renal tubular response to proteinuria. Multiplealternatively spliced transcript variants have been found for CTSL.
    
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- Properties
  - Protein Name
    
    Cathepsin L, CTSL1, Cathepsin L1, Major Excreted Protein, MEP, EC 3.4.22.15, CATL, EC 3.4.22.
    
    Source
    
    E. coli
    
    Type
    
    Recombinant Proteins
    
    Purification
    
    Greaterthan 90% as determined by SDS-PAGE.
    
    Formulation
    
    CTSL protein solution (1mg/ml) containing 20mM Tris-HCl (pH 8.0) and 10% glycerol.
    
    Storage
    
    Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please avoid freeze thaw cycles.
    
    * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

CTSL Recombinant Protein

CTSL Recombinant Protein

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