Name: CST3 Native Protein
Price: Inquiry

- Overview
  - Cystatins are a superfamily of cysteine proteinase inhibitors found in both plants and animals. They comprise a group of proteinase inhibitors, widely distributed in tissues and body fluids, and form tight complexes with cysteine proteases such as cathepsin B, H, L and S. Cystatin C, a secreted molecule of this family, is of interest from biochemical, medicine and evolutionary points of view. Cystatin C, with molecular weight of 13260 Da, is composed of 120 amino acids, lacks carbohydrate and has two disulfide bridges located near the carboxyl terminus. Cystatin C is increased in patients with malignant diseases, and is related to the insufficiency of renal function and appears to be a better marker than creatinine. On the other hand, low levels of cystatin C involve cause the breakdown of the elastic laminae and, subsequently, the atherosclerosis and abdominal aortic aneurysm.
    
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- Properties
  - Protein Name
    
    Cystatin-C, Cystatin-3, Neuroendocrine basic polypeptide, Gamma-trace, Post-gamma-globulin, CST3, MGC117328.
    
    Source
    
    Human urine
    
    Type
    
    Recombinant Proteins
    
    Purification
    
    Greater than 96% as determined by SDS PAGE.
    
    Formulation
    
    Lyophilized from 0.02M NH4HCO3. May contain traces of buffer salts.
    
    Storage
    
    Human Cystatin-C although stable at 4°C for 1 week, should be stored at -15°C. Please avoid freeze-thaw cycles.
    
    * For Research Use Only. Not for use in diagnostic/therapeutics procedures.
- Applications
  - Application Description
    
    Use of a 0.02M NH4HCO3 buffer is recommended.

CST3 Native Protein

CST3 Native Protein

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