Name: Crospovidone
Price: Inquiry

- Overview
  - Product Description:
    C494178, Crospovidone, is unsurpassed in its performance and versatility as a superdisintegrant in formulations. It combines different mechanisms to achieve rapid tablet disintegration at low concentrations (1-5%). Due to its viscoelasticity, C494178 is highly compactable, resulting in robust tablets with increased tensile strength and reduced friability. Scanning electron microscope images of C494178 show a granular and porous structure with a large surface area. It enhances the dissolution of poorly soluble drug actives and due to its non-ionic property, it does not bear any risk of interaction with cationic APIs. C494178 is available in two particle sizes to serve different application requirements.
    
    Benefits:
    • Rapid disintegration at low concentrations (1-5%)
    • Functions via a combination of disintegration mechanisms (wicking, shape recovery, and swelling), thus imparting its unsurpassed versatility as a superdisintegrant in formulations
    • Suitability for use in direct compression, wet granulation, and dry granulation
    • Increased tablet tensile strength and reduced friability due to high compressibility
    • No gel formation even at higher concentrations (10%) – ideal for ODTs
    
    Please contact us at for specific academic pricing.
- Properties
  - Alternative Name
    
    N-VINYL-2-PYRROLIDONE | 88-12-0 | 1-vinylpyrrolidin-2-one | N-Vinylpyrrolidone | 1-Vinyl-2-pyrrolidone | 9003-39-8 | 1-Vinyl-2-pyrrolidinone | N-Vinyl-2-pyrrolidinone | Povidone | Vinylpyrrolidone | N-Vinylpyrrolidinone | 1-ethenylpyrrolidin-2-one | 2-Pyrrolidinone, 1-ethenyl-
    
    CAS Number
    
    25249-54-1
    
    Molecular Formula
    
    (C6H9NO)n
    
    Molecular Weight
    
    111.14
    
    Other Properties
    
    Melt Point (°C): >300°C
    
    Storage
    
    Room temperature
    
    Shipping
    
    Normal
    
    SMILES
    
    C=CN1CCCC1=O
    
    InChi
    
    InChI=1S/C6H9NO/c1-2-7-5-3-4-6(7)8/h2H,1,3-5H2
    
    InChi Key
    
    WHNWPMSKXPGLAX-UHFFFAOYSA-N
    
    PubChem CID
    
    6917
    
    Others
    
    IUPAC Name: 1-ethenylpyrrolidin-2-one
    
    Hazard Information
    
    Signal: Danger
    Hazard Statements: H335,H351,H373,H302,H318,H312,H332
    Precautionary Statements: P261,P280,P302+P352,P321,P405,P501,P264,P260,P271,P270,P304+P340,P403+P233,P362+P364,P330,P203,P264+P265,P301+P317,P305+P354+P338,P318,P317,P319
    WGK Germany: 1
    
    * For research use only. Not for use in human or animal.

Crospovidone

Crospovidone

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