Name: COX17 Polyclonal Antibody (1.2 mg/mL) for IHC, ELISA
Price: 253.00 USD

Overview
- Gene Accession: NP005685
  
  Please contact us at for specific academic pricing.
  
  Background
  
  Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes a protein which is not a structural subunit, but may be involved in the recruitment of copper to mitochondria for incorporation into the COX apoenzyme. This protein shares 92% amino acid sequence identity with mouse and rat Cox17 proteins. This gene is no longer considered to be a candidate gene for COX deficiency. A pseudogene COX17P has been found on chromosome 13.
Properties
- Host
  
  rabbit
  
  Antibody Type
  
  polyclonal
  
  Isotype
  
  IgG
  
  Reactivity
  
  human; mouse
  
  Immunogen
  
  Synthetic peptide of human COX17
  
  Purification
  
  Antigen affinity purification
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
  
  Storage
  
  Store at -20°C. Avoid freeze-thaw cycles.
  
  Concentration
  
  1.2 mg/mL
  
  Antigen
  
  COX 17, COX17, COX17 cytochrome c oxidase assembly homolog (S. cerevisiae), COX17 cytochrome c oxidase assembly homolog, COX17 homolog cytochrome c oxidase assembly protein, COX17, cytochrome c oxidase assembly protein cox17 homolog, Cytochrome c oxidase copper chaperone, Human homolog of yeast mitochondrial copper recruitment, MGC104397, MGC117386, OTTHUMP00000215284, OTTHUMP00000215285 (UniProt:Q14061)
  
  * For reference only.