ω-Conotoxin GVIA

- Overview
  - ω-Conotoxin GVIA, a peptide compound, is a neurotoxin that acts as a potent antagonist of voltage-activated N-type Ca2+
    channels and of neurotransmitter release at neuronal synapses. Its
    antagonistic activity is attributed to a tyrosine residue at position
    13. Does not bind to dihydropyridine- or verapamil-binding sites. Also
    reported to inhibit ATP-induced inward currents mediated by P2X2/X3
    receptors (IC50 = 21.2 nM for P2X3 and 3.84 µM for P2X2/X3 heterooligomeric receptors).
    
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- Properties
  - Categories
    
    Peptides
    
    CAS Number
    
    106375-28-4
    
    Molecular Formula
    
    C120H182N38O43S6
    
    Molecular Weight
    
    3037.35
    
    Purity
    
    ≥98%
    
    Storage
    
    Powder: store in -20°C freezer for up to three years, store in 4°C freezer for up to two years
    In solvent: store in -80°C freezer for up to six months, store in -20°C freezer for up to two months
    
    Shipping
    
    Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
    
    SMILES
    
    C[C@](O)([H])[C@@](/N=C(O)/[C@](/N=C(O)/[C@]1([H])C[C@](O)([H])CN12)([H])CC3=CC=C(O)C=C3)([H])/C(O)=N/[C@@](/C(O)=N/[C@@](/C(O)=N\[C@@](/C(O)=N\[C@@](C(O)=N)([H])CC4=CC=C(O)C=C4)([H])CSSC[C@@](N=C(O)[C@](N=C(O)[C@](N=C(O)[C@](N=C(O)[C@](N=C(O)[C@]5([H])C[
    
    * For research use only

ω-Conotoxin GVIA

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