Name: COMT Polyclonal Antibody (1.02 mg/mL) for WB, IHC, ELISA
Price: 253.00 USD

Overview
- Calculated MW: 30 kDa
  Observed MW: Refer to figures
  Gene Accession: BC011935
  
  Please contact us at for specific academic pricing.
  
  Background
  
  Catechol-O-methyltransferase catalyzes the transfer of a methyl group from S-adenosylmethionine to catecholamines, including the neurotransmitters dopamine, epinephrine, and norepinephrine. This O-methylation results in one of the major degradative pathways of the catecholamine transmitters. In addition to its role in the metabolism of endogenous substances, COMT is important in the metabolism of catechol drugs used in the treatment of hypertension, asthma, and Parkinson disease. COMT is found in two forms in tissues, a soluble form (S-COMT) and a membrane-bound form (MB-COMT). The differences between S-COMT and MB-COMT reside within the N-termini. Several transcript variants are formed through the use of alternative translation initiation sites and promoters.
Properties
- Host
  
  rabbit
  
  Antibody Type
  
  polyclonal
  
  Isotype
  
  IgG
  
  Reactivity
  
  human
  
  Immunogen
  
  Fusion protein of human COMT
  
  Purification
  
  Antigen affinity purification
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
  
  Storage
  
  Store at -20°C. Avoid freeze-thaw cycles.
  
  Concentration
  
  1.02 mg/mL
  
  Antigen
  
  Catechol O methyltransferase, Catechol O-methyltransferase, COMT, COMT, EC 2.1.1.6 (UniProt:P21964)
  
  * For reference only.

Applications

Application

WB; IHC; ELISA

Application	Dilutions
WB	1:500-1:2000
IHC	1:25-1:100
ELISA	1:5000-1:10000

COMT Polyclonal Antibody (1.02 mg/mL) for WB, IHC, ELISA

COMT Polyclonal Antibody (1.02 mg/mL) for WB, IHC, ELISA

Background

We Also Recommend

CPNE3 Polyclonal Antibody

CRABP1 Polyclonal Antibody (2.1 mg/mL) for WB, IHC, ELISA

DMC1 Polyclonal Antibody