Cobicistat - Amerigo Scientific

- Overview
  - Cobicistat is an inhibitor of human cytochrome P450 3A enzymes (CYP) with no antiviral activity. Cobicistat is used in the treatment of HIV-1 infection, as an alternative to ritonavir, to increase the half-life of antiviral medications (von Hentig, 2016). Cobicistat acts as a booster by selectively inhibiting the hepatic degradation of the drugs, for example, in the pharmacological regime against HIV-1, which often includes protease inhibitors, such as, darunavir, atazanavir, and lopinavir, or the integrase inhibitor elvitegravir (Deeks, 2014).
    
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- Properties
  - Categories
    
    Enzyme Modulators
    
    Alternative Name
    
    (3R,6R,9S)-2-Methyl-13-[2-(1-methylethyl)-4-thiazolyl]-9-[2-(4-morpholinyl)ethyl]-8,11-dioxo-3,6-bis(phenylmethyl)-2,7,10,12-tetraaz atridecanoic acid 5-thiazolylmethyl ester; Tybost; GS-9350
    
    CAS Number
    
    1004316-88-4
    
    Molecular Formula
    
    C40H53N7O5S2
    
    Molecular Weight
    
    776.03 g/mol
    
    MDL Number
    
    MFCD18251449
    
    Note
    
    There is no hazardous surcharge associated with this product.
    There is no special packaging charge associated with this product.
    
    * For research use only. Not for human or veterinary use