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Overview
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Calculated MW: 151 kDa
Observed MW: 275 kDaPlease contact us at for specific academic pricing.
Background
The product of this gene is an essential upstream regulator of checkpoint kinase 1 and triggers a checkpoint arrest of the cell cycle in response to replicative stress or DNA damage. The protein is also required for efficient DNA replication during a normal S phase. Multiple transcript variants encoding different isoforms have been found for this gene.
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