CIB1 Mouse Monoclonal Antibody

CIB1 Mouse Monoclonal Antibody

Catalog Number:
A001449891ZEN
Mfr. No.:
Zen-220107
Price:
  • Size:
    100μl
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      • Overview
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          Background

          CIB1(also designated calcium and integrin binding 1 or calmyrin),with 191-amino acid protein(about 21kDa), belongs to the calcium-binding protein family.CIB1 is known to interact with DNA-dependent protein kinase and may play a role in kinase-phosphatase regulation of DNA end joining.CIB1 is an EF-hand-containing protein that binds multiple effector proteins, including the platelet alpha(IIb)beta(3) integrin and several serine/threonine kinases and potentially modulates their function.CIB1 regulates platelet aggregation in hemostasis through a specific interaction with the alpha(IIb) cytoplasmic domain of platelet integrin alpha(IIb)beta(3). CIB1 is also ubiquitously expressed activating and inhibiting protein ligand of the InsP3R.

      • Properties
        • Host
          mouse
          Isotype
          IgG
          Reactivity
          human
          Clone
          5A1F5E12; 5A1H7E12
          Immunogen
          Purified recombinant fragment of CIB1 expressed in E. Coli.
          Purification
          Ascitic Fluid
          Conjugate
          Unconjugated
          Formulation
          Ascitic fluid containing 0.03% sodium azide.
          Storage
          Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
          Antigen
          (Gene ID:10519; UniProt:Q99828)

          * Research Use Only Product (RUO). Not for Diagnosis or Therapeutic Use.

      • Applications
        • Application
          IHC-P
        • Application Dilutions
          IHC 1/100-1/200

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