Cholinergic Receptor, Muscarinic 4 - ExpressMAX™ Human GPCR ORF Clones

Like other muscarinic receptors, the M4 receptor is widely expressed in different regions of the forebrain. Interestingly, M4receptor is coexpressed with D1 dopamine receptors in a specific subset of striatal projection neurons. Those receptors have opposing effects on the activity of adenylyl cyclase: activation of M4 receptor has an inhibitory effect on adenylyl cyclase whereas D1 has an increasement of intracellular cAMP levels.

Includes:
ExpressMAX™ GPCR ORF Clones (Cat. No. -A)
– 15 µg ExpressMAX™ Mammalian Expression Vector (1 mg/mL).
ExpressMAX™ GPCR ORF Clones (Cat. No. – B)
– Vector as transformed Bacteria in stab culture or a Glycerol Stock format.
Mammalian Transfection Kits (Cat. No. – PLUS)
– 15 µg ExpressMAX™ Mammalian Expression Vector (1 mg/mL).
– 0. 2 mL CANFAST™ Transfection Reagent.

Please contact us at for specific academic pricing.