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CFL2 Recombinant Protein

CFL2 Recombinant Protein

Catalog Number:
P001415591ABE
Mfr. No.:
Abe32-3516
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  • Size:
    20 µg
    Quantity:
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      • Overview

        • CFL2 Human Recombinant produced in E. Coli is a single, non-glycosylated polypeptide chain containing 186 amino acids (1-166 a.a.) and having a molecular mass of 20.9kDa. CFL2 is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. CFL2 protein is a member of the actin-binding proteins ADF family which contains 1 ADF-H domain. Cofilin is a broadly distributed intracellular actin-modulating protein which binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. Defects in the CFL2 gene are the cause of nemaline myopathy type 7 (NEM7).

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      • Properties
        • Protein Name
          Cofilin-2, Cofilin- muscle isoform, CFL2, NEM7.
          Source
          E. coli
          Type
          Recombinant Proteins
          Purification
          Greater than 90.0% as determined by SDS-PAGE.
          Formulation
          CFL2 protein solution (1mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 2mM DTT, 10% glycerol and 50mM NaCl.
          Storage
          Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.

          * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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