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Overview
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Background
Cholesteryl ester transfer protein (CETP) is a circulating metabolic enzyme that transports cholesterol from the arteries to the liver. CETP converts cholesteryl esters from antiatherogenic high density lipoproteins (HDLs) to proatherogenicapolipoprotein B (apoB)-containing lipoproteins, including very low-, intermediate-, and low-DLs. Efficient transfer and exchange of cholesteryl esters and triglycerides between the lipoprotein classes of human plasma is necessary to maintain healthy arteries.
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