Name: CEP57 Polyclonal Antibody (0.4 mg/mL) for WB, IHC, ELISA
Price: 253.00 USD

Overview
- Calculated MW: 57 kDa
  Observed MW: Refer to figures
  Gene Accession: BC039711
  
  Please contact us at for specific academic pricing.
  
  Background
  
  This gene encodes a cytoplasmic protein called Translokin. This protein localizes to the centrosome and has a function in microtubular stabilization. The N-terminal half of this protein is required for its centrosome localization and for its multimerization, and the C-terminal half is required for nucleating, bundling and anchoring microtubules to the centrosomes. This protein specifically interacts with fibroblast growth factor 2 (FGF2), sorting nexin 6, Ran-binding protein M and the kinesins KIF3A and KIF3B, and thus mediates the nuclear translocation and mitogenic activity of the FGF2. It also interacts with cyclin D1 and controls nucleocytoplasmic distribution of the cyclin D1 in quiescent cells. This protein is crucial for maintaining correct chromosomal number during cell division. Mutations in this gene cause mosaic variegated aneuploidy syndrome, a rare autosomal recessive disorder. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
Properties
- Host
  
  rabbit
  
  Antibody Type
  
  polyclonal
  
  Isotype
  
  IgG
  
  Reactivity
  
  human; mouse; rat
  
  Immunogen
  
  Full length fusion protein
  
  Purification
  
  Antigen affinity purification
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
  
  Storage
  
  Store at -20°C. Avoid freeze-thaw cycles.
  
  Concentration
  
  0.4 mg/mL
  
  Antigen
  
  Centrosomal protein 57kDa, Centrosomal protein of 57 kDa, Cep57, Cep57 protein, CEP57, FGF2 interacting protein, FGF2-interacting protein, KIAA0092, MVA2, PIG8, Proliferation inducing protein 8, Testis specific protein 57, Testis-specific protein 57, Translokin, TSP57 (UniProt:Q86XR8)
  
  * For reference only.

Applications

Application

WB; IHC; ELISA

Application	Dilutions
WB	1:500-1:2000
IHC	1:25-1:100
ELISA	1:5000-1:10000

CEP57 Polyclonal Antibody (0.4 mg/mL) for WB, IHC, ELISA

CEP57 Polyclonal Antibody (0.4 mg/mL) for WB, IHC, ELISA

Background

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