Name: cdc25C(Phospho-Ser216) Antibody
Price: 483.00 USD

Overview
- Please contact us at for specific academic pricing.
  
  Background
  
  cdc25C is highly conserved during evolution and it plays a key role in the regulation of cell division. The encoded protein is a tyrosine phosphatase and belongs to the Cdc25 phosphatase family. It directs dephosphorylation of cyclin B-bound CDC2 and triggers entry into mitosis. It is also thought to suppress p53-induced growth arrest. Multiple alternatively spliced transcript variants of this gene have been described, however, the full-length nature of many of them is not known.
Properties
- Host
  
  rabbit
  
  Antibody Type
  
  polyclonal
  
  Isotype
  
  IgG
  
  Reactivity
  
  human
  
  Immunogen
  
  Peptide sequence around phosphorylation site of serine 216 (S-P-S(p)-M-P) derived from Human cdc25C.
  
  Purification
  
  Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatography using non-phosphopeptide.
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  
  Storage
  
  Store at -20°C. Avoid freeze / thaw cycles.
  
  Concentration
  
  1.0 mg/mL
  
  Antigen
  
  CDC25M1;MPIP3 (Gene ID:995; UniProt:P30307)
  
  * This product is for Research Use Only.

Applications

Application

WB; IHC; IF

Application	Dilutions
WB	1:500-1:1000
IHC	1:50-1:100
IF	1:100-1:200

cdc25C(Phospho-Ser216) Antibody

cdc25C(Phospho-Ser216) Antibody

Background

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