CD68 Polyclonal Antibody (1 mg/mL) for WB, IF

CD68 Polyclonal Antibody (1 mg/mL) for WB, IF

Catalog Number:
A001511387RED
Mfr. No.:
RD86787A
Price:
$416
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      • Overview
        • Calculated MW: 8kDa/13kDa/15kDa/16kDa/18kDa
          Observed MW: 16KDa

          Please contact us at for specific academic pricing.

          Background

          This gene encodes a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins. The protein is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages. Alternative splicing results in multiple transcripts encoding different isoforms.

      • Properties
        • Host
          rabbit
          Antibody Type
          polyclonal
          Isotype
          IgG
          Reactivity
          human; mouse; rat
          Immunogen
          Recombinant fusion protein of human CD68
          Purification
          Affinity purification
          Conjugate
          Unconjugated
          Formulation
          PBS with 0.01% thiomersal,50% glycerol,pH7.3.
          Storage
          Store at -20°C Valid for 12 months. Avoid freeze-thaw cycles.
          Concentration
          1 mg/mL
          Antigen
          CD68, GP110, LAMP4, SCARD1 (Gene ID:968; UniProt:P34810)

          * For reference only.

      • Applications
        • Application
          WB; IF
        • Application Dilutions
          WB 1:500-1:2000
          IF 1:50-1:200

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