Name: CD45 Extracellular (HiLyte Fluor647 Conjugated) Antibody
Price: Inquiry

Overview
- Sensitivity: Endogenous
  
  Please contact us at for specific academic pricing.
  
  Background
  
  The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. Alternatively spliced transcripts variants of this gene, which encode distinct isoforms, have been reported. [provided by RefSeq, Jun 2012]
Properties
- Host
  
  Rabbit
  
  Antibody Type
  
  polyclonal
  
  Isotype
  
  IgG
  
  Reactivity
  
  Human, Mouse
  
  Immunogen
  
  Synthetic peptide / Extracellular domain corresponding to Human CD45
  
  Conjugate
  
  HiLyte Fluor647
  
  Storage
  
  PBS (pH 7.4), 0.2% BSA, 0.1% Gelatin, 0.1% NaN3 was added as a preservative
  This product is stable for 12 months when stored undiluted between 2°C and 8°C, protected from prolonged exposure to light. Do not freeze.
  
  * For research use only.