Name: CD3 (mouse specific), Monoclonal Antibody
Price: 200.00 USD

Overview
- Sensitivity: Endogenous
  Target name: CD3 (mouse specific), monoclonal
  Area: Immune cell / T cell marker
  
  Please contact us at for specific academic pricing.
  
  Background
  
  The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. [provided by RefSeq, Jul 2008]
Properties
- Host
  
  Rat
  
  Antibody Type
  
  monoclonal
  
  Isotype
  
  IgG2a
  
  Reactivity
  
  Mouse
  
  Clone
  
  mAb
  
  Immunogen
  
  Synthetic peptide / Extracellular domain corresponding to Mouse CD3
  
  Storage
  
  Phosphate-buffered solution, pH 7.2, containing 0.025% ProClin 300, 20% Glycerol.
  Store at -20°C.
  
  * For research use only.