CBY1 cDNA

- Overview
  - Beta-catenin is a transcriptional activator and oncoprotein involved in the development of several cancers. CBY1 encoded by this gene interacts directly with the C-terminal region of beta-catenin, inhibiting oncogenic beta-catenin-mediated transcriptional activation by competing with transcription factors for binding to beta-catenin. Two transcript variants encoding different isoforms have been found for this gene.
    
    PRODUCT INFORMATION
    Antigen Species: Human
    NCBI Accession No: NP_056188.1
    RNA Reference Number: NM_015373.3
    OMIM Number: 607757
    Chromosome Location: 22q12
    cDNA size: 381bp
    Vector description: This shuttle vector contains the complete ORF. It is inseted Nde I to Xho I. The gene insert contains multiple cloning sites which can be used to easily cut and transfer the gene and recombination site into your expression vector.
    
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- Properties
  - Protein Name
    
    arb1, C22orf2, CBY, HS508I15A, PGEA1, PIGEA-14, PIGEA14
    
    Type
    
    cDNAs
    
    Formulation
    
    Lyophilized
    
    Storage
    
    Store the plasmid at -20°C.
    
    Sequence
    
    Nucleotide Sequence: ATGCCTTTCT TTGGGAATAC GTTCAGTCCG AAGAAGACAC CTCCTCGGAA GTCGGCATCT CTCTCCAACC TGCATTCTTT GGATCGATCA ACCCGGGAGG TGGAGCTGGG CTTGGAATAC GGATCCCCGA CTATGAACCT GGCAGGGCAA AGCCTGAAGT TTGAAAATGG CCAGTGGATA GCAGAGACAG GGGTTAGTGG CGGTGTGGAC CGGAGGGAGG TTCAGCGCCT TCGCAGGCGG AACCAGCAGT TGGAGGAAGA GAACAATCTC TTGCGGCTGA AAGTGGACAT CTTATTAGAC ATGCTTTCAG AGTCCACTGC TGAATCCCAC TTAATGGAGA AGGAACTGGA TGAACTGAGG ATCAGCCGGA AGAGAAAATG A
    Translation Sequence: MPFFGNTFSP KKTPPRKSAS LSNLHSLDRS TREVELGLEY GSPTMNLAGQ SLKFENGQWI AETGVSGGVD RREVQRLRRR NQQLEEENNL LRLKVDILLD MLSESTAESH LMEKELDELR ISRKRK.
    
    * For research use only. Not intended for human, diagnostics or veterinary use.
- Applications
  - Application Description
    
    (1) Centrifuge at 7000rpm for 1 minute. (2) Carefully open the vial and add 100ul of sterile water to dissolve the DNA. Each tube contains approximately 10ug of lyophilized plasmid.

CBY1 cDNA

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