Cardiogreen

- Overview
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    Background
    
    Cardiogreen, also known as indocyanine green, is a nontoxic tricarbocyanine dye, with a peak spectral absorption at 790 nm. Cardiogreen administered intravenously rapidly binds to its principle carrier, plasma protein, and then becomes confined to the vascular space. Cardiogreen has been commonly used in medical diagnostics for measuring cardiac output, liver blood flow, and hepatic function, as well as for ophthalmic angiography. In addition, cardiogreen can also be used as a photosensitizer in the photodynamic therapy (PDT) for treating diseases like periodontal infections.
    
    1. "Indocyanine green solution". NIH. National Cancer Institute. Retrieved 20 August 2021.
    2. Gharesi S, Pourhajibagher M, Chiniforush N, et al. Effect of photodynamic therapy based on indocyanine green on expression of apoptosis-related genes in human gingival fibroblast cells. Photodiagnosis and Photodynamic Therapy , 2017, 19: 33-36.
- Properties
  - Categories
    
    A fluorescent cyanine dye used for a variety of medical diagnostics
    
    Alternative Name
    
    Foxgreen; IC Green; Indocyanine green; sodium 4-(2-((1E,3E,5E,7E)-7-(1,1-dimethyl-3-(4-sulfonatobutyl)-1H-benzo[e]indol-2(3H)-ylidene)hepta-1,3,5-trien-1-yl)-1,1-dimethyl-1H-benzo[e]indol-3-ium-3-yl)butane-1-sulfonate
    
    CAS Number
    
    3599-32-4
    
    Molecular Formula
    
    C43H47N2NaO6S2
    
    Molecular Weight
    
    774.96
    
    Purity
    
    98.00%
    
    Solubility
    
    insoluble in EtOH; ≥17.17 mg/mL in H2O; ≥27.65 mg/mL in DMSO
    
    Storage
    
    Store at -20°C
    
    SMILES
    
    O=S(CCCCN(C1=C(C/2(C)C)C3=CC=CC=C3C=C1)C2=C\C=C\C=C\C=C\C4=[N+](CCCCS([O-])(=O)=O)C5=C(C6=CC=CC=C6C=C5)C4(C)C)([O-])=O.[Na+]
    
    * For Research Use Only